Scientists discover a protein switch that burns fat and blocks new fat cells

Scientists discover a protein switch that burns fat and blocks new fat cells

Modern weight loss medications have transformed obesity treatment, helping many people lose significant amounts of weight. But these drugs often come with an important drawback: They can also reduce muscle mass. Now, researchers have uncovered a biological mechanism that may one day help address that challenge while also boosting the body’s ability to burn fat….

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The Guardian view on the Ockenden maternity review: lifting standards must be the number one priority | Editorial

The Guardian view on the Ockenden maternity review: lifting standards must be the number one priority | Editorial

The painful familiarity of key themes in Donna Ockenden’s review of maternity care failures must not detract from the urgency around this issue. The 400-page report published on Wednesday is a shocking catalogue of what went wrong at Nottingham university hospitals NHS trust. Its contents range from a excruciating case study of the errors leading…

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The Guardian view on Labour’s leadership: Andy Burnham has a story. He must also have a plan | Editorial

The Guardian view on Labour’s leadership: Andy Burnham has a story. He must also have a plan | Editorial

Political careers often end when circumstances demand qualities that a politician cannot supply. That seems especially true of Sir Keir Starmer. On Monday, he stepped down as Labour leader, hours before Andy Burnham arrived at Westminster to take his seat as MP for Makerfield. Sir Keir’s achievements were real. He won a large parliamentary majority in 2024, provided…

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